QIAGEN CLC Genomics Workbench 26

CLC Genomics Workbench 26 is a comprehensive bioinformatics software package from QIAGEN Digital Insights, providing an easy-to-use graphical interface for analyzing genomic, transcriptomic, and other biological data . It supports daily bioinformatics work through individual tools and streamlined workflow automation .

Current Version | 26.0.4 (latest) / 26.0.2 (stable)

Key New Features in Version 26

Public Health & Clinical Genomics

• MAFFT Aligner: New support for more accurate multiple sequence alignment .
• Ridom/EnteroBase cgMLST Schemes: Enhanced support for core genome MLST analysis, specifically for public health labs and pathogen surveillance .

Clinical & Liquid Biopsy Workflows

• Hereditary Disease & Liquid Biopsy Workflows: New support for Twist and QIAseq panels, aiding in clinical research for hereditary conditions and circulating tumor DNA analysis .

Synthetic Biology & Construct Design

• Construct Generator: A new tool for synthetic biology, allowing the design and generation of genetic constructs for biotech research .

Workflow & Usability Enhancements

• Faster FASTA Import: Substantially faster loading of FASTA files (.fa, .fsa, .fasta) .
• Template Workflow Updates: QIAseq Panel Analysis Assistant now supports custom panel configurations; RNA-Seq workflow includes Sample Level Heat Maps .
• PDF Report Customization: Exported reports can now be saved without a front page or table of contents .
• De Novo Assembly for Long Reads: New “Trim windows” and “Minimum coverage” settings for Oxford Nanopore and PacBio CLR reads, improving assembly quality for low-coverage samples .
• Reference Data Manager: Enhanced search functionality, clearer labeling, and download status indicators .
• Annotate with GFF/GTF/GVF: Supports multiple external files for annotation

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